The Biological Dosimetry Laboratory
(LDB) is located at Fontenay-aux-Roses, in the Paris region and managed
by Céline Baldeyron. In 2008, the laboratory obtained accreditation from
COFRAC for its cytogenetic analysis activity.
Biological dosimetry is the assessment of the impairment of an irradiated person based on the radiation-induced variations of certain biological parameters. Biological dosimetry is complementary to clinical symptomatology and physical dosimetry.
Context and research themes
The Biological Dosimetry Laboratory is in the field of main research thematique "Biological doimetry and indicators".
- Set up an operational organization and means enabling assessments to be performed by biological dosimetry in case of a radiological or nuclear accident;
- Perform biological dosimetry assessments, within the above mentioned organization or as a service, for proven or suspected radiation overdoses in the case of a radiological or nuclear accident, or in the medical sector and professional sector (workers, patients), in agreement with the policy defined by the Institute;
- Study the operational application of new biological dosimetry methods to reconstitute the dose received by a person exposed to ionizing radiation of any type (external, internal, heterogeneous, localized, past);
- Participate in the research carried out within the radiology and epidemiology service on biological diagnostic and prognostic indicators making it possible to better estimate radiation induced damage, and to study their operational application.
Specialties and researchers
Céline Baldeyron, head of laboratory
Delphone Dugué, technician
Amélie Fréneau, research engineer
Éric Grégoire, research engineer
Gaëtan Gruel, researcher
Cécile Martin-Bodiot, technician
Sandrine Roch-Lefevre, researcher
Aurélie Vaurijoux, research engineer
Pascale Voisin, technician
Facilities and techniques
- Conventional and fluorescence microscopes
- An image analysis system developed by a French company specializing in medical imagery and validated by the LDB with regard to the biological dosimetry part
- Two flow cytometers, including a cell analyzer-sorter
- An automatic detection system for chromosomal anomalies
- A confocal microscope
- Culture rooms with laminar flow extractors