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IRSN, Institut de radioprotection et de sûreté nucléaire

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Enhancing Nuclear Safety


Research

Research Units

Experimental Radiotoxicology and Radiobiology Laboratory (LRTOX)


 

The Experimental Radiotoxicology and Radiobiology Laboratory (LRTOX) is located on sites at Pierrelatte and Fontenay-aux-Roses. It comprises 24 personnel including 7 researchers (physical chemists, biologists and veterinarians), several student doctorands and post-doctorates.

 


 

 

Context and research themes

 

The mission of LRTOX is to perform all types of experimental studies enabling acquisition of the basic data necessary to assess the levels and consequences of incorporation of radionuclides.

In particular, it coordinates the “health” input to the ENVIRHOM project, the objective of which is to describe the phenomenon of chronic accumulation of nuclides and to determine their effects on organisms.

 

 

Research axes


The main skills of the laboratory are:

  • The study of physical chemical characteristics of industrial compounds at workstations,
  •  
  • The biokinetic study of radionuclides after incorporation by ingestion, inhalation or injury,
  •  
  • Determination of the biological effects resulting from accumulation of incorporated radionuclides,
  •  
  • Determination at molecular level of the fixation and retention mechanisms for radionuclides in organisms.

 

 

 

Research team

 

Karine Tack, head of laboratory

Jean-Marc Bertho, researcher

David Cohen, researcher

Christelle Durand, biology researcher

Teni Ebrahimian Chiusa, researcher

Christelle Elie, technician

Céline Gloaguen, biology technician

Stéphane Grison, research engineer

Yann Gueguen, researcher

Christelle Ibanez, researcher

Dimitri Kereselidze, analysis technician

Audrey Legendre, researcher

Philippe Lestaevel, researcher

Maâmar Souidi, researcher

Alice Bontemps, PhD student (2016-2019)
Dalila Lebsir, PhD student (2015-2018)

 

 

Facilities and techniques

 

  • Rodent house in controlled zone
  • Atmospheric sampling apparatus
  • Inhalation enclosures
  • Scanning and transmission electron microscopes
  • X-ray diffraction
  • Autoradiography systems
  • HPLC, EC, ultracentrifuge
  • Alpha, beta, gamma radio-chemistry

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Chercheur en radiotoxicologie  Crédits : Thomas Gogny/IRSN

Contact

Karine Tack, head of laboratory

 

IRSN/PSE-SANTÉ/SESANE
Experimental Radiotoxicology and Radiobiology Laboratory (LRTOX)
BP 17
92260 Fontenay-aux-Roses
France

 

By Phone: +33 (0)1 58 35 83 48


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