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IRSN, Institut de radioprotection et de sûreté nucléaire

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Enhancing Nuclear Safety


Research

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Development of a Personalised Dosimetric Tool for Radiation Protection in case of Internal Contamination and Targeted Radiotherapy in Nuclear Medicine.

Sophie CHIAVASSA, doctorate thesis of the University of Paul Sabatier (Toulouse) speciality radiological and medical physics, 227p, defended on the 12th december 2005.

Summary

Current internal dosimetric estimations are based on the MIRD formalism and used standard mathematical models. These standard models are often far from a given patient morphology and do not allow to perform patient-specific dosimetry.
The aim of this study was to develop a personalised dosimetric tool, which takes into account real patient morphology, composition and densities. This tool, called OEDIPE, a French acronym of Tool for the Evaluation of Personalised Internal Dose, is a user-friendly graphical interface. OEDIPE allows to create voxel-based patient-specific geometries and associates them with the MCNPX Monte Carlo code. Radionuclide distribution and absorbed dose calculation can be performed at the organ and voxel scale.
OEDIPE can be used in nuclear medicine for targeted radiotherapy and in radiation protection in case of internal contamination.


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