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Dependence of the dose estimate on the time pattern of intake by the example of tritiated water intakes


Congress title : 6th Workshop on Internal Dosimetry of Radionuclides 
Congress location : Montpellier
Congress date :02/10/2006
Journal title : Radiation Protection Dosimetry 127 issue 1-4 Pages : 387-391

Document type > *Congrès/colloque

Keywords >

Research Unit > IRSN/DRPH/SDI/LEDI

Authors > BLANCHARDON Eric, MOLOKANOV Andrey

Publication Date > 01/11/2007

Summary

The uncertainties related to activity measurement and time pattern of intake in routine monitoring of internal exposure are considered through the example of tritiated water intakes. For this purpose, a combination of intake-to-bioassay and bioassay-to-intake calculations with Monte Carlo integration technique is introduced as a method of investigation. The time pattern of intake and the measured activity are defined as random input quantities. The probability density functions (PDFs) of the input quantities are defined and a Monte Carlo integration is performed to obtain the PDF of the output quantity which is either the value of intake estimated from a measured value of activity or the estimated activity from a given value of intake. Different possible estimates of the intake are considered: some represent the parameters of the PDF of the output quantity, others are derived from the commonly used constant chronic, ICC, and mid-point, I1/2, methods. The combinations of activity and intake estimates that would provide a stable estimate of the initial intake in intake-to-bioassay and bioassay-to-intake calculations were studied. Several intake estimates satisfying this requirement can be chosen depending on the task to be solved by adjusting the proper activity estimate.

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