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Dependence of the dose estimate on the time pattern of intake by the example of tritiated water intakes


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Titre du congrès : 6th Workshop on Internal Dosimetry of Radionuclides
Ville du congrès : Montpellier
Date du congrès :02/10/2006
Titre de la revue : Radiation Protection Dosimetry 127 issue 1-4 Pages : 387-391

Type de document > *Congrès/colloque

Mots clés >

Unité de recherche > IRSN/DRPH/SDI/LEDI

Auteurs > BLANCHARDON Eric, MOLOKANOV Andrey

Date de publication > 01/11/2007

Résumé

The uncertainties related to activity measurement and time pattern of intake in routine monitoring of internal exposure are considered through the example of tritiated water intakes. For this purpose, a combination of intake-to-bioassay and bioassay-to-intake calculations with Monte Carlo integration technique is introduced as a method of investigation. The time pattern of intake and the measured activity are defined as random input quantities. The probability density functions (PDFs) of the input quantities are defined and a Monte Carlo integration is performed to obtain the PDF of the output quantity which is either the value of intake estimated from a measured value of activity or the estimated activity from a given value of intake. Different possible estimates of the intake are considered: some represent the parameters of the PDF of the output quantity, others are derived from the commonly used constant chronic, ICC, and mid-point, I1/2, methods. The combinations of activity and intake estimates that would provide a stable estimate of the initial intake in intake-to-bioassay and bioassay-to-intake calculations were studied. Several intake estimates satisfying this requirement can be chosen depending on the task to be solved by adjusting the proper activity estimate.