The Radiochemistry, Speciation and Imaging Laboratory (LRSI) is located at Fontenay-aux-Roses, in the Paris region. Managed by Céline Bouvier-Capély, the laboratory regularly welcomes university students, PhD students and post-doctorates.
Context and research themes
The LRSI's research themes are:
- internal contamination treatment,
- SIMS technique.
The LRSI's main mission is to:
- Improve (in terms of sensitivity and response time) the radio toxicological analysis methods of actinides in the biological environment, in order to optimize monitoring of workers in the nuclear industry exposed to an internal contamination risk by alpha emitters;
- Study, using “ Secondary Ion Mass Spectrometry” (SIMS), the elementary distribution profiles on the tissue and cell scale in organs after internal contamination, for better understanding of the radionuclide fixation mechanisms and health consequences. This work will contribute to refine the existing dose calculation models;
- As a consequence of the IRSN missions quoted in various ministerial orders and decrees, contribute to the advice that the IRSN gives, for example, for accreditation of French Medical Biology Analysis Laboratories (LABM);
- Within the current radiation protection context, extend its field of competence to surveillance in the medical environment (professionals and patients) and to that of the population.
Céline Bouvier-Capély, head of laboratory
Valérie Holler, researcher
Géraldine Landon, engineer
Alexandre Legrand, technician
Annabelle Manoury, technician
Guillaume Phan, research engineer
David Suhard, technician
Facilities and techniques
- Secondary Ion Mass Spectrometer (SIMS)
- Mass spectrometer coupled with induced plasma (ICP-MS)
- Alpha spectrometry measurement systems
- Beta counters
Partnership and research networks
The LRSI works in collaboration with universities (Lyon I, Paris School of Chemistry), the Xavier Bichat medical faculty, the Chatenay-Malabry pharmacy faculty and nuclear medicine services (CHI Le Raincy – Montfermeil, Saint-Antoine Hospital, Beaujon APHP Hospital). It collaborates with numerous international institutes within the framework of research contracts jointly financed by the European Union. The LRSI also participates in production of AFNOR and ISO standards in the field of internal dosimetry