Last update on November 2019
Context and research themes
The mission of LRTOX is to perform all types of experimental studies enabling acquisition of the basic data necessary to assess the levels and consequences of incorporation of radionuclides.
In particular, it coordinates the “health” input to the ENVIRHOM project, the objective of which is to describe the phenomenon of chronic accumulation of nuclides and to determine their effects on organisms.
Research topics
The main skills of the laboratory are:
- The study of physical chemical characteristics of industrial compounds at workstations,
- The biokinetic study of radionuclides after incorporation by ingestion, inhalation or injury,
- Determination of the biological effects resulting from accumulation of incorporated radionuclides,
- Determination at molecular level of the fixation and retention mechanisms for radionuclides in organisms.
Research team
Dmitry Klokov, head of laboratory
Laurence Roy, researcher
Jean-Marc Bertho, researcher
David Cohen, researcher
Christelle Durand, biology researcher
Teni Ebrahimian Chiusa, researcher
Christelle Elie, technician
Céline Gloaguen, biology technician
Stéphane Grison, research engineer
Christelle Ibanez, researcher
Dimitri Kereselidze, analysis technician
Philippe Lestaevel, researcher
Alice Bontemps, PhD student (2016-2019)
Léo Mace, PhD student (2018-2021)
Nicolas Rey, PhD student (2017-2020)
Céline Serrano, PhD student (2017-2020)
Facilities and techniques
- Rodent house in controlled zone
- Atmospheric sampling apparatus
- Inhalation enclosures
- Scanning and transmission electron microscopes
- X-ray diffraction
- Autoradiography systems
- HPLC, EC, ultracentrifuge
- Alpha, beta, gamma radio-chemistry
