Quick and efficient extraction of uranium from a contaminated solution by a calixarene nanoemulsion
A. Spagnul et al. / International Journal of Pharmaceutics 398 (2010) 179–184
This work aims to evaluate the efﬁciency of a calixarene emulsion for uranium extraction from a contaminated solution prior to apply such a delivery system to uranium skin decontamination. For this purpose, various experimental parameters that can inﬂuence the efﬁciency of the calixarene emulsion on uranium extraction were determined. The results show that the calixarene nanoemulsion effect can be observed after a very short time of contact with uranium-contaminated solution (5min) and that it is still efﬁcient in case of small volumes of contaminated solution. The pH of the contaminated solution was found to be the most important parameter affecting the calixarene nanoemulsion efﬁciency with a dramatic reduction of the uranium extraction rate in case of acidiﬁcation of the contaminatedmedium. This lack of efﬁciency can be overcome by buffering the nanoemulsion continuous phase. The obtained results reveal that the calixarene nanoemulsion could represent a promising system for the emergency treatment of uranium cutaneous contamination.