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La mortalité par cancer des travailleurs du Commissariat à l'énergie atomique.


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M. Telle-Lamberton, D. Bergot, M. Gagneau, E. Samson, J.M Giraud, M.O Néron and P. Hubert, American journal of industrial medicine, 45:34 (2004).

Type de document > *Article de revue

Mots clés > radioprotection, Epidémiologie des risques professionnels., rayonnements ionisants

Unité de recherche > IRSN/DRPH/SRBE/LEPID

Auteurs > TELLE-LAMBERTON Maylis

Date de publication > 01/04/2004

Résumé

 

Background:
All causes and cancer mortality of 58320 workers employed at the Commissariat à l’Energie Atomique (CEA) between 1946 and 1994 was compared with that of the general population in a retrospective cohort study.

Methods:

Standardized Mortality Ratios (SMR) were computed with reference to the French national population
Results:

4809 deaths occurred between 1968 and 1994. A Healthy Worker Effect is observed for men (SMR=0.57 CI90%=[0.56;0.59]) and for women (SMR=0.72 CI90%=[0.67;0.77]). 9 sites of cancer death were found to be in statistically significant deficit among men, none among women. An excess of pleural cancers is observed among men (SMR=1.79, CI90%=[1.27;2.45]) and of malignant melanoma (SMR=1.50, CI90%=[1.04;2.11]). An excess of breast cancer is observed among women on the borderline of significance (SMR=1.14, CI90%=[0.94; 1.37]).

Conclusions:

Excesses observed will have to be related to occupational exposures in the on-going cohort study on French nuclear workers which includes a retrospective exposures assessment.